Source #1
""Using metoprolol and clonidine together may lower your blood pressure and slow your heart rate. Using these medications together can cause a slow heartbeat, headaches, dizziness, or feeling like you might pass out. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.""

Source#2
""On the contrary, beta adrenergic blockers may also potentiate the hypertensive response to withdrawal of clonidine in patients receiving concomitant clonidine and beta-adrenergic blocker. If a patient is treated with clonidine and Metoprolol Tartrate concurrently, and clonidine treatment is to be discontinued, stop Metoprolol Tartrate several days before clonidine is withdrawn. Rebound hypertension that can follow withdrawal of clonidine may be increased in patients receiving concurrent beta-blocker treatment.""

Comments:
It appears that Metoprolol can cause hypertension if Metoprolol and Clonidine are taken together and Clonidine is discontinued. An interesting situation. Although this isn't your situation, it shows that an unexpected reaction can occur if both are taken together under specific circumstances. If I were you, I'd be sure to:

• See another doctor for a 2nd opinion.
• Carefully tell him or her of my research.
• The above potential interaction between Metoprolol and Clonidine as detailed under specific circumstances.
• The possibility of Idiosyncratic Reactions, where medications, or hypothetically combinations of medications, produce reactions opposite to the intended reaction.
• I would divulge all medications, supplements, herbs, vitamins, alcohol, tobacco, and other items used or consumed. There's a chance that something isn't being metabolized as intended, doctors need to know everything a person is exposed to.
• I'd consider looking for a good Endocrinologist.

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