according to the respiratory therapist I spoke with, you can’t use the soclean with the trilogy 100 as the Ozone will damage the trilogy machine and that is not covered in the waranty so you could be out $11,000 for a new Trilogy 100

@maryjoanncosta, @johnbishop John you crack me up with the "own personal butler" comment above. I know your comment is from over a year ago, but I would just like to add that the SoClean customer support is awesome. I had broken a piece from the adapter for my old CPAP machine. I went to the website and noticed that they did not sell just the little hose piece with the diffuser I needed, with or separately from the adapter I had broken. I had used my SoClean2 for several years at that point, but since they did not offer the hose and diffuser I needed, they sent me free of charge, including shipping, the broken piece and a different adapter that came with the hose and diffuser attached even though I did not need that adapter. I only needed the little hose and diffuser from it. That is great customer service in my opinion!!