I also have g.i. issues - fructose malabsorption, lactose intolerance and visceral hypersensivity - and had finally gotten everything under control until I got a 1/2 dose infusion of Reclast almost 3 months ago. After that I had the worst constipation I've ever had in my life. I was so bound up and bloated my g.i. doctor did an Xray to see if there was a blockage and there wasn't. A also had a blood test for lipase, a pancreatic enzyme, and my lipase was way below normal. The uptake: I had to take laxatives every day and increase the amount of Creon I'm taking. The problem with the constipation went away after about a month, but the indigestion issues are still going on. G.I. issues are listed as a possible side effect of the drug, and probably if you already have them the drug worsens them immensely. If you look up Reclast on the Mayo Clinic site it lists many, many possible side effects including g.i. issues. So, it is a myth that the infusion will bypass stomach issues.