I had a Reclast infusion on 3/13/15 after having Osteopenia for a number of years and taking a combination of Boniva and Fossamax for 5 years. Starting that day, I have had tingling or small spasms in my feet and lower legs without stop. I briefly had mild aches, mild muscle pain and a headache, but they went away. I sometimes have learned to ignore the spasms. Sometimes I can't sleep, although "Restless legs" seems to help for a bit. My doctor sent me for an ultrasound (negative), for a painful electromyocardiogram (negative) to check my nerves and for a vein check. I have moderate vein disease and had outpatient surgery for it. When I sit too long, my legs get pins and needles. The doctor could not find anything wrong with me. It has been 4 years! Now my arms get too. Has anyone else had this issue or have any suggestions on how to at least reduce the sensations? I did not have another Reclast infusion and just learned I don't quite have osteoporosis yet. I was diagnosed with it 2 years ago, but got a better DEXA scan with a fancier 2 leg machine, and found out I still have osteopenia for the moment. I was recently thrilled to find a few new lactose free foods that I can eat, since I am lactose intolerant. Boar's Head lactose free cheddar and Fairlife milk. Still searching for answers.