My sister has been on the trilogy for almost two years now, as I'm writing this she is her last few hours of life. Her doctor have given her 6 months to live on at least 4 occasions. First started about 6 years ago. This machine has helped to keep her around far longer than anyone could have guessed. She is on 30lpm @90%. She has had to be on the trilogy or an airvo (which she use so she could eat). We have found this to be a wonderful machine. What we found when we were trying to get one is that they are very difficult to get for every day home use. You have to get them through a medical phacilialty. Nursing home, hospice or hospital. It is very much like a ventalor but is NON-invasive.