This started the beginning of the 7th grade at the onset of puberty and now he is a freshman (or should be but isn't attending school ) with his IEP they are allowing him to do online but he really wont or cant do that work. He says he feels like nothing will ever help him etc.... I am hopeful this will make a difference. His psychiatrist said from the genomind genetic report it makes sense why the meds he has been on have not worked -- due to his genetic makeup and I assume and his MTHFR gene mutations.