Connect
Hip Hip Hooray…It’s Chemo Day! 🎈🎈🎈
Heading off to the Chair in a couple hours for first dose of Taxotere (docetaxel). Low dose of 65mg/m2. Will increase to 75mg/m2 for the remainder if tolerated. I told them to put a port in because I am not an easy stick for an IV but, they said they never port on the first infusion in case it's not tolerated. We'll see how that goes.
Had a CT c/a/p late yesterday. No results yet. Have a bone scan tomorrow. Hope I don't puke on the table. 🤮
Very little sleep last night, no not anxious, back is starting to scream again. I'm guessing the bone scan is going to light up from about L3 down. On the positive side, maybe it'll work out and I can sleep in the Chair. I'll report back later. Have a great day, all!
Oh... and in keeping with treatment tradition from last year's RT...
Today's shirt...
Like
Helpful
HugInterested in more discussions like this? Go to the Prostate Cancer Support Group.
Connect
Well...this can't be good. Today's (10/26) blood work:
ALP 268 - up from 208 on 10/5
PSA 46.45 - up from 26.47 on 9/10
Numbers are certainly not going in the right direction. This, coupled with a new L4 lesion seems to say this Taxotere stuff is working about as well as ADT/ARSI did. We'll see what the oncology brain trust has to say about it at tomorrow's visit when I ask him, "What else you got, boss? Oh, and by the way, time for some tramadol." 😎
-
Like -
Helpful -
Hug
4 Reactions@mjp0512 https://seekingalpha.com/news/4657148-johnson-and-johnson-reports-75-percent-tumor-response-rate-novel-prostate-cancer-therapy
I think some new therapy trial program might be in order for you...also, you might try Alpha Lipoic Acid - it is easy to take OTC antioxident that in some trials has shown tendency to inhibit PC cell reproduction...I take one 3-5 times a week..take with food as it can upset your stomach..Google it and see if it might be something you want to try. It wont hurt you otherwise, even if it doesnt help inhibit the PC spread.
Good luck amigo..keep us up to date.. we care!
-
Like -
Helpful -
Hug
3 Reactions@mjp0512
UGHHHHH - I HATE YOUR CANCER !!!!! What the heck ? 😖 How stubborn it can be ??? Maybe it needs to be shocked by T mega-dose infusion ? Or they can use those new isotopes that are not Pluvicto ? I agree with @xahnegrey40 - how about some study participation ? Also, I think I read that Kytruda (sp. ???) or something like that works for some patients and perhaps there is some immunothreapy study close by ? One never knows - look at this : https://pmc.ncbi.nlm.nih.gov/articles/PMC4214463/ And why nobody continued to explore that is beyond me ?! Even if it helped only 10% of cases - I am sure that patients would like to try and be those 10% !!!!!
I am so sorry mjp, but MO tomorrow will probably have some good ides 🍀🍀🍀 and I hope that Tramadol works well and that you are at least in zero pain *hugsssss
Let us know what MO says and try to rest as much as you can 🍁...
-
Like -
Helpful -
Hug
3 Reactions@xahnegrey40 = Thank you my friend, and thanks for the link.
@surftohealth88 - Hi surf. Yea, need to do something, Sleep is becoming more elusive by the day. Thanks for the hugs, thanks for the link, but most importantly, thanks for the PUPPIES! 😁
-
Like -
Helpful -
Hug
1 Reaction@mjp0512 Hey bud, sucks what you are going thru.
Can you get that new lesion zapped now or do you have to wait until chemo is done?
Sounds like some rules might need to be broken - some oncologists are rigid to the extreme and follow the cookbook of bombing the lesions with chemo and only then will they do SBRT.
I think you need to take your walking stick upside somebody’s head…
Phil
@heavyphil - Hi Phil. MO already voiced a willingness to send me to RT, especially if I need some pain resolution. Seems to me with rising numbers and new lesions, this chemo stuff isn't working anyway but maybe the norm is more than 2 cycles is needed to make a determination. I'll find out in a couple hours and let y'all know.
-
Like -
Helpful -
Hug
11 ReactionsWell… ain’t that a kick in the head. The lab jumped the gun on the PSA test. It was not supposed to be done until after cycle 3 because if there is going to be a PSA flare, it will happen through cycle 2. So…the PSA increase is either a flare or it’s real and chemo isn’t working. Doc was hesitant in authorizing another cycle because of my side effect profile, but I convinced him I can make it through another and, “besides, how else do we know for sure if it’s working or not?” So…he signed off.
RO visit scheduled for next month. Case file already flagged so they can pre-plan what can and can’t be targeted.
An interesting tidbit I learned in talking with the doc. In a case like mine where 2 conflicting genetic markers occur (in my case SPOP = good & TP53 = bad), the bad one always wins.
Oh, and apparently, Tramadol is not my GUO’s drug of choice, so Oxy it is.
Pharmacist, “Hi Mike. Can I answer any questions about the prescription?”
Me, “No thanks, Ray. I was a teenager in the 60’s. I’m pretty sure I know more about these kinds of drugs than you do.” 🤣😂😎
-
Like -
Helpful -
Hug
6 Reactions@mjp0512
Just continued thoughts and best wishes to you.
You are going thru so much.
Hoping the chemo is working and radiation can work on your spine.
-
Like -
Helpful -
Hug
1 Reaction@charlesprestridge - Thank you so much, charles,
-
Like -
Helpful -
Hug
1 Reaction