@petitefitsmartfemale If you follow the recommendation of the Japanese Ministry of Health, which has studied MK-4 extensively, the daily recommended dosage of MK-4 is 45 mg. I think I read somewhere that recommended treatment would be 15 mg 3x/day because of MK-4's short half-life.

High dosage MK-4 is not available as a supplement by many companies here. It is also a rather expensive supplement. I have found it in 15 mg/capsule form and that's what I'm taking even though it's below the 45 mg dosage. I could easily increase that to 3x/day to reach 45 mg but that's an expensive option.

I looked into Life Extensions' Q&A section for their Mega Vitamin K2 and saw that another customer had posted a question about divided doses. Here's what LE said:

"Since Mk-4 has a short half life, it has been suggested to split the 45 mg per day dose into 2 or 3 times per day. Is it ok to open the capsule and pour some out into a food product, and split the capsule? Is the taste tolerable? Thank you for your help.
Asked by Joyce 2 years ago
Verified Reply - Pamela, Clinical Information Expert
You can, and it is still possible that you derive benefits from the nutrients. However, the product was not designed for ingestion in this manner so we cannot state that the efficacy will be the same as when the capsules are swallowed whole. Also, some may find the taste slightly bitter or objectionable because the product is very potent."
https://www.lifeextension.com/vitamins-supplements/item02417/mega-vitamin-k2-high-potency-for-strong-bones
I am tempted to try the Life Extension product. Open the capsule and divide its contents. Dosages may not be identical but they would at least have some spread over time. For me, there's an advantage in opening the capsule because I have a swallowing disorder so can't swallow large capsules or pills.

Having said that, though, I have been taking 15 mg of MK-4 for about a month. I feel something is better than nothing. But a quick search suggests that lower dosages of MK-4 may have positive results too:
https://pubmed.ncbi.nlm.nih.gov/23702931/
"Menaquinone-4 (MK-4) administered at a pharmacological dosage of 45 mg/day has been used for the treatment of osteoporosis in Japan. However, it is not known whether a lower dose of MK-4 supplementation is beneficial for bone health in healthy postmenopausal women. The aim of this study was to examine the long-term effects of 1.5-mg daily supplementation of MK-4 on the various markers of bone turnover and bone mineral density (BMD)."

"These results suggest that low-dose MK-4 supplementation for 6-12 months improved bone quality in the postmenopausal Japanese women by decreasing the serum ucOC and pentosidine concentrations, without any substantial adverse effects."

The Japanese appear to be doing more research on MK-4 than we are in the U.S.