Does anyone else get night sweats, extreme cold or heat on TYMLOS?

alidamc, there is no proof that Tymlos affects the adrenal gland. There is unproven mention of this rare possibility with the somewhat similar Forteo from 2010. I only mention it because of you symptoms and because you are looking at the thyroid you may as well look at the adrenal gland. I hope it isn't Tymlos and proves to be a simple fix.

I have no clue what causes it. I would like to know if this happens to anyone else?

Yes, I have been experiencing that as well, I have been taking tymlos 9 months, wasn't sure if related to Tymlos or aging. I sure hope the hair loss and this is worth the bone building. Maybe all will change after the 18 month end period!

@wkruse thanks for your reply. Let’s report new side effects. The first month, I didn’t have any. 2nd month (hair loss), 6 weeks, waking up drenched in the morning. Now at beginning of 3rd month, I get SO hot about after an hour after taking it, I eat or drink something cold. Thinking about changing the time I take it to afternoons instead of bedtime. Waking up drenched is not as often but can happen at any time.
This is new to me because I never had any menopause symptoms. If this is what menopause is like, I was really lucky. I can’t keep the temperature right in my house as fall approaches. It’s old and taking time to warm it up when I need to.
Thanks so much for responding!

@wkruse I just read an article in the Washington Post that says iron deficiency can cause hair loss. Maybe the drug is affecting our iron levels. I am going to ask my PCP if I can start taking it again because I really don’t eat as well as I should.
https://www.hematology.org/newsroom/press-releases/2026/ash-sets-new-standards-for-diagnosing-iron-deficiency

@wkruse my sister, an internist, just told me to try this:
Ferrous gluconate is well tolerated.
Easier on the stomach.
You need at least 27 mg of elemental iron.

@alidamc, yes, I have been waking up during the night drenched in sweat but this is one of the minor side effects of Tymlos. I am in my third month and needed to take a two week break since my symptoms were so debilitating. The two week break will end this week so I will try to slowly start taking it again but at an incremental pace. I have severe osteoporosis (-3.7 bmd) so this development is very disappointing if I cannot tolerate Tymlos in the long run. Prayers would be so appreciated. Take care.

Same here, waking with night sweats, and then times I am freezing. Sweats started a couple months after starting Tymlos. I have always been a little on the freezing side, but more extreme at times now, I hope all of these symptoms will go away after the Tymlos. I am really counting on this med to improve my bones. I guess a small price to pay if it works. Now into month 5. Have not seen any hair loss as some have noted.

@paxbar I get night sweats as well, but less so if I take the injection earlier in the day. If I inject later into the evening, I have difficulty falling asleep due to overheating and my sleep is not very satisfying.

Yes, I have been experiencing that as well, but I am also hyperthyroid. I asked PC doctor to have me start HRT. Not sure if he changes his mind, as he ran blood work. I also might need thyroid meds adjust. I have been having hot flashes for twenty years, as soon as I had an ovary removed. Not sure if Tylmos is the cause. But, Tymlos is causing leg and belly swelling.