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Letrozole & weight gain

Breast Cancer | Last Active: Oct 12 9:20pm | Replies (14)

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@mir123 Thank you for sharing your experience. I had very bad joint pain from anastrazole and had to move exemestane. Now with this weight gain, I want to try letrozole. I hope it doesn't bad joint pain.

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Replies to "@mir123 Thank you for sharing your experience. I had very bad joint pain from anastrazole and..."

@lesliek808 I wish you all the best with this. I gather there can be bad side effects with all of the aromatase inhibitors, but it is good to see if one works better for you. I've been very lucky with the letrozole--no side effects and I credit it with keeping the breast cancer at bay.

@lesliek808 I have only taken Letrozole (for 18 months until it stopped working). Definitely caused joint pain for me, including de Quervains in my left wrist which requires me to wear a brace to help ease the pain. Also had trigger fingers/thumb in both hands which elected to have surgery for. No fun. I am sure each of the aromatase inhibitors will affect each person differently. I am now diabetic after being on Letrozole. Studies show it is definitely linked to the development of diabetes.
Gained weight as well. I am 71. Good luck on your search for finding something you can live with ( the side effects), sincerely, not being sarcastic!