@alidamc i’m 12 months on Tymlos now. I am so needle phobic that when I had my ears pierced I fainted. I thought I could never do this, i.e. self inject. But now it’s just something I do and only on the rarest occasion, does it actually hurt when the needle is going in which means I’ve selected a bad spot. What helps me the most is to pinch enough skin where I’m inserting the needle and I guess that allows the needle to go in without touching any muscle. I believe that is why it would hurt. On very rare occasion, I get some blood, but otherwise, as long as I hold the needle steady, and I prop it up with my index finger from the other hand, there’s absolutely nothing uncomfortable. Once and only once I injected in a very bad place because I developed a hematoma that took weeks to dissipate. It could’ve been a bruise, but it was at least 3 inches Across and I had to avoid that side of my tummy. I also tried the thigh and that hurt. Not enough fat in the prescribed injection location, which of course is off label. I also read that thigh absorption is not as good with thigh injections so I don’t do that any longer. It’s not as though I look forward to self injecting, but I no longer dread it.