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I have been on Lyrica/pregabalin for several years. The pain was getting worse and the neurologist kept increasing the dosage until I reached 450 mg daily (he said that increasing to 600 mg daily is not going to help the pain). I still have quite a bit of pain: burning and muscle weakness. I also take 600 mg alpha lipoic acid daily. Has anyone experienced this? Either I developed tolerance to the Lyrica or my nerves just keep getting worse and the Lyrica is not effective anymore. I am 79 yo male.

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Replies to "I have been on Lyrica/pregabalin for several years. The pain was getting worse and the neurologist..."

@plenty55 I don’t know what state you live in but I’m in CT. I sat with a pharmacist at a medical mj dispensary and told them I have “bee sting,” nerve damage from a surgery when I was opened for ALIF fusion. They picked a concentrate that’s in a plastic syringe. (1) rice grain dose in an empty capsule knocked it out completely. Zero side effects except giggling. I use to take (1) capsule BID now it’s every other day. While it great for radiculopathy and stinging, it doesn’t help the cervical myelomalacia I’m also suffering from. I haven’t found anyone to teach me what to expect since the surgery is just slowing progression. I had an awful night last night and it’s wearing me out.
If anyone has this I’d love to learn how you cope. Tizanidine wakes me up exactly 6 hours after taking it so they switched me to Flexoril which doesn’t seem sufficient for these GIANT spasms that consume my shoulders, neck arms and my right bicept is screaming. Thank you. I’m in CT.