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Psma addition

Prostate Cancer | Last Active: Sep 26 3:50pm | Replies (21)

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Could be not sure… however, the chemical they’re using is called LUTETIUM – 177. I believe it’s the radioactive shot to give you every six weeks for metastatic prostate cancer that is not castrate resistant.

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Replies to "Could be not sure… however, the chemical they’re using is called LUTETIUM – 177. I believe..."

@whatthef - Yep, that's Pluvicto. PSMAddition was a trial specifically adding Pluvicto to ARPI. The recent FDA approval your Dr is referring to (7/31/26) is for castrate sensitive patients. Pluvicto was already approved for castrate resistant disease.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01092-5/abstract
https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/170879-fda-approves-pluvicto-for-psma-positive-metastatic-hormone-sensitive-prostate-cancer-mhspc.html

@whatthef Lu 177 is Pluvicto. If you search the posts on "Pluvicto," you can read many entries that should answer your questions.

@whatthef Also, it is an infusion, not a shot, and it can be given to both castrate sensitive and castrate resistant men.