Besremi was just approved (end of August 2026) by the FDA for treating ET, so that might change insurance coverage going forward. I am 62 and have been on Besremi now since July of 2025. I was on 200 and initially had some fatigue on injection day and dry mouth, but the fatigue and dry mouth did improve over time, especially when my dosage was reduced to 150. I do have a lingering rash around the injection site, but Besremi has been very effective in bringing my numbers into the normal range. After a year, my doctor was able to reduce the frequency of injections to only once a month instead of every other week. Best of luck to you with your treatment. Positive, healing energy to you and lots of hugs.