Good luck, Bob. Wheel1's comments are spot on, although it has taken me about 6 months to realize that variability in each case is reality. I think it's of specific value to note that Wheel1's comment regarding 80% vs 72% success rate - and what the doctors may recommend as a result, regardless of the side effects of the approach - is something you'll need to consider. I had that exact experience with my doctors - they recommended aggressive treatment based on the RADICALS-HD study results. I read the study several times, and then pursued a second opinion from Ohio State's James Center. I came away with a much different opinion from their doctors as to the best approach for my situation. I continue to try to find the "best" approach for me.

I wish you the best as you navigate this journey.