@jeanadair123 lots of pain especially in my feet. I have neuropathy and the ADT made it much worse. I have great fatigue, occasional mild hot flashes, very weak legs as well as just generally feeling like crap. I consider this the new normal for me and I accept it. It could be much worse. As a matter of fact it was worse when I was having chemo infusions. I asked my oncologist how long I would be on Orgovyx and Nubeqa, his response was permanently. I do hope things smooth out for your husband. These are serious drugs and there are a host of side effects.