@nohrt4me I went to a pulmonologist two days ago and he believes I have possibly pulmonary fibrosis now.. cause.... LONG TERM use of Hydroxyurea. Please look at other options if you can depending on how long you plan to be around. Hydroxyurea is not the best solution long term, but maybe only short term. I have since switched to JAKAFI per the recommendation of the Mayo clinic consult. IT has changed my life, now that I am almost 70. It seems my doctors did not tell me that I would eventually have poor lung performance due to the long term use of hydroxyurea. First I have heard of it, and I have been getting treatment for over 35 years. Come on ! explain this stuff will ya? So frustrated at times, but carrying on anyway!