Hi I am researching a similar issue to what you experienced and wrote about Dec 2025. 62.5 started 100 mg progesterone, 0.050 dottie patch and vag estrodoil cream April 26 2026. Within 1 week I felt amazing - I was a good sleeper but prior to starting I was waking up 1-2 x a nite to pee and if I sneezed I would have to squeeze my legs to not drip pee. I am athletic active healthy not overweight 5'6" female last period age 54. I was late to get on HRT because in 2018 when my prior ob gyn was trying insurance would not approve progesterone (terrible I know here we are in USA w health care insurance lack of womens health knowledge). Back to my current issue - I have felt incredible like HRT was the magic glue for my entire body - my waist size is smaller and my body composition positively changed even my hair and skin. Then something changed with my sleep up again 1 time. Then Dottie patch shortage 0.050 so provider upped to 0.75 in 2 weeks felt like crap. Labs showed estrodoil went from 66 to 45 but she is like anything over 20 is in range (I am SO sick of hearing this BS) I was at .50 before HRT June 1 2026 labs were amazing after starting in April 2026 - why on earth do these practioners say this when my body and labs were in sync feeling great. Now something is off - not sure if its progesterone or estrodiol - any thoughts ?