I have been using Duloxetine for approximately two years. I built up to 120mg a day (60mg/am and 60mg/pm) however, I found this level - although helpful with the pain, left me totally brain fogged. After chatting things over with GP - we decided to titrate back to just 60mg in the morning - along with a low dose Buprenorphine patch. However, the patch has been gradually increased to 15mm and with the addition of paracetamol three or four times a day - - it has made the pain much more bearable. I also have recently been diagnosed with four broken vertebrae T12, L1, L4 and L5 - which led to a Dexa Scan confirming Osteoporosis. I also have osteoarthritis in my lower spinal facet joints - plus, I have replacement left and right hips - obviously, all these extra issues, together with fibro, literally are a pain in the butt and the back - as well as in all the other parts of my aching body !! If all that wasn’t enough, at the end of February, I underwent open heart bypass surgery (CABG) that included a collapsed lung! No real surprise as I have Asthma - and am 80 years young. What I wasn’t expecting, was in April, for my lungs to decide to take on fluid, for it to hang around and then provide the perfect breeding ground for pneumonia. At this point I was briefly back in hospital where they filled me with a couple of heavy duty antibiotics that quickly allowed me to return home to recuperate. Having cleared a good percentage of the gunk from the lungs, a CT Scan in May - has shown several suspicious 6mm nodules - so the radiologist has scheduled me in for another CT scan in September . You wouldn’t think that my nick-name is Lucky would you!!🇬🇧🤣😂🤣😂