Side effects of exemestane (Aromasin)

Posted by Young@65 @happyat65, Feb 12, 2023

Has anyone had higher blood sugar since taking exemestine? Any other side effects. My oncologist changed me to exemestine from anastrozide. I have been on it only 5 days, but the muscle and joint aches are here. Headaches every day.

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Thankyou so much for this information. It helps knowing others are out there with advice and experience of tbis medication. I’m seeing my surgeon in a couple of weeks and will suggest switching drug if possible.

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Profile picture for 16bernie @16bernie

I too started exemestane last month joint pain, extreme tiredness and now teeth painful and dry mouth (which can be a sign of diabetes). Has anyone had this side effect? Oncologist has me off meds for 2-weeks to make sure this new side-effect is due to medication.

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@16bernie Blocking estrogen has driend absolutely everything....skin, mouth, eyes, hair. I take the exemestane at night now and that helps with the fatigue. The joint and muscle pain remains an issue even after almost 4 years. I decided to just continue with this drug rather than switch to another with different side effects.

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I understand completely. On Anastrozole, had total hysterectomy, now hair dry, thinning miserable. Thinking of changing to Tamoxifen so I can use hormone cream to get some relief. Surgeon wouldn't put m e on it while I was an Anastrozole. Gonna talk to my Oncologist.

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Profile picture for mspass @mspass

@16bernie Blocking estrogen has driend absolutely everything....skin, mouth, eyes, hair. I take the exemestane at night now and that helps with the fatigue. The joint and muscle pain remains an issue even after almost 4 years. I decided to just continue with this drug rather than switch to another with different side effects.

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I'm the person who gets extremely oily skin from exemestane. 6 months of a face like an oil slick. Hair and ears also. Now at exactly 6 months on exemestane I had a 5 day migraine. Have not had them since I was on Anastrozole for 8 months 3 years ago ( I did a total of 3 1/2 yrs until another cancer popped up). They all felt like hormonal ones I had before menopause. My nurse seems to think there is no correlation with the length of time I've been on exemestane. I have a call in for discussion. I'm not convinced. I'm 73 so I guess the excess oil is a good thing but I could not put up with 5 day migraines. As we can see by this chat group, we all react differently to this drug.

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