@conniemarie

I was on 1000mg daily for PV. My labs dropped weekly. I also developed side effects, severe itching, especially when I laid down, headaches, brain fog was worse, bloody nose, mouth sores, was very fatigued. I was miserable. Weekly MD lowered my dose weekly ,not because of my symptoms but my labs continued to drop until they were at alert level low. That's when hydrea was discontinued. That was the end of January. It took until June for my labs to return to normal levels. In July my labs hit treatment levels. I have a new MD who thankfully started me on Jakafi. I just started it yesterday and hopefully I will have the good response others have experienced. I'm not knowledgeable about ET but have experience with hydrea. Im not trying to scare you, you may not have the same experience and be able to tolerate a higher dose. If you do the higher dose just pay attention to your symptoms and work with your MD. Good luck and best wishes.