Testosterone recovery after 6 mos Orgovyx

Posted by bob1955 @bob1955, Aug 14 9:22am

Age 70, 4+3, PSA 10, 4 months post EBRT, 6 weeks post ADT
Testosterone is mostly back after six weeks. Before: 505, after: 450
Not too bad for an old guy. No desire yet, though.

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@carlsbadguy Looks like you are responding nicely to the Orgovyx. Good results for 6 weeks. How did you know the prostate shrunk, did you have an MRI?

I know with Crib & IDC it puts you in a high risk category but I would look at some studies showing one year of ADT had not much difference than 18 months to 2 years. Did your docs mention anything about having an HDR Brachy boost along with the RT?

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@copyman The most prominently cited study of EBRT plus brachy boost that found no difference between 6 months of ADT vs. 30 months of ADT is the TRIP study.

Patients staged T3b and higher were excluded, i.e. patients were excluded if there was proof of cancer outside the gland. TRIP did not consider the extent of cribriform or IDT.

When you say "studies" do you know of any other studies of how long ADT is effective on patients treated with EBRT plus brachy boost?

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