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What is the major difference between pregabalin and gabapentin?

Posted by mikead63 @mikead63, Apr 18, 2025

I have idiopathic peripheral neuropathy (diagnosed in January of this year). I was prescribed gabapentin 2-3 hours before bedtime. At this point I am at 600mg which helps while I know it's a low dose for many, at this point it's fine for me. I had not heard of pregabalin until today when I was researching info. in Pharmacy Times. I know that pregabalin is quickly absorbed while gabapentin is absorbed around 3 hours post dose. My question is: IS ANYONE ON PREGABALIN? If so, how is that working out??

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culebra2024 | @culebra2024 | 12 hours ago
In reply to @blowerk1216 "My research shows that pregablin has been tested more than gabapentin and shows more success for..." + (show)
Profile picture for blowerk1216 @blowerk1216

My research shows that pregablin has been tested more than gabapentin and shows more success for pain relief. However it has to be at least 300 mg per day to be more effective than the placebo, its effectiveness increases at the 600 mg per day level.

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@blowerk1216 However it has to be at least 300 mg per day to be more effective than the placebo, its effectiveness increases at the 600 mg per day
Do you mean gabapentin or pregablin?

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bajjerfan | @bajjerfan | 9 hours ago
In reply to @culebra2024 "@blowerk1216 However it has to be at least 300 mg per day to be more effective..." + (show)
Profile picture for culebra2024 @culebra2024

@blowerk1216 However it has to be at least 300 mg per day to be more effective than the placebo, its effectiveness increases at the 600 mg per day
Do you mean gabapentin or pregablin?

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@culebra2024

He meant the R form of alpha-lipoic acid.

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