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getting back to normal after ADT

Posted by lacraig1 @lacraig1, 1 day ago

I had 3 shots of Lupron and one pill of abiraterone acetate (general Zytiga) to suppress my testosterone. I stopped this, because it was simply too disruptive. Last shot was early December 2025. I still have this disruption. I don't sleep well. I keep waking up, feeling like my hormones are racing around in my body Nap often. I feel lousy much of the day. I'm thinking it's affecting my heart. Want to see an endocrinologist. Anybody else having/had a hard time getting back to normal?

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lacraig1 | @lacraig1 | 9 hours ago
In reply to @jeffmarc "@lacraig1 You’re right I did not mention sleep as a problem, but so many people on..." + (show)
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@lacraig1
You’re right I did not mention sleep as a problem, but so many people on here Have complained about the fact that while they’re on ADT, they can’t get decent sleep. Very hard to get to sleep for some of those people.

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@jeffmarc falling asleep is easy it's the constant waking up that's troubling.

Often when I wake up, some of my body parts are all wired up, and I know I'm not going to fall asleep any time soon. So I go work on the computer or watch Netflix

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roseat | @roseat | 2 hours ago
In reply to @lacraig1 "@roseat I couldn't last 3 months on Lupron. He wanted 3 years. Your PSA is undetectable..." + (show)
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@roseat I couldn't last 3 months on Lupron. He wanted 3 years. Your PSA is undetectable because you are on Lupron. Once you are off, it's a new ball game. My poor sleep is affecting my health. Possibly my heart. I have ED too, but I can achieve an orgasm in about a minute. I have hot flashes and all around lousiness.

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@lacraig1 Have you seen a radiation oncologist or an Urologist for a first or second opinion? Have you had a PSMAPET/CT Scan? Since being on Lupron I now also take Rosuvastatin tablets.

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northoftheborder | @northoftheborder | 49 minutes ago

The problem with Zytiga is that it's a first-gen ARSI that requires taking a steroid with it, and steroids themselves can cause or exacerbate side-effects for many people.

The second-gen ARSIs ("lutamides") do not require a steroid, have fewer side-effects for many people, and are somewhat more effective, but they're also *very* expensive (especially in the U.S.), so insurers probably try to steer doctors away from them.

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