Hi, I was on Anagrelide for over 10 years and only because my haematologist left the clinic I was seeing, the new haematologist put me on HU. They could not give me Anagrelide. So for about 18 months I was on HU. My hair thinned out quite a bit and being out in the sun, even with sun protection and proper clothing, I could feel the sun burning my skin. Uncomfortable feeling to say the least. I also suffered more from fatigue during that time. My second haematologist left and I aksed my GP to refer me to the Holman Clinic so I could go back on Anagrelide. After a couple of months my platelet levels are within normal again. While I was on HU for 18 months, they never got back down to normal range. I am so happy that I am now back on Anagrelide. Side effects: fatigue, but not as bad as when on HU.
As with any medication, tell your doctor of any side effects you may get. Good luck and hugs.