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Hesitant on starting Hydrea for ET Jak 2

Blood Cancers & Disorders | Last Active: 4 minutes ago | Replies (23)

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@mdramsey48
Yes on interferon - I have been listening to many podcasts promoting it over HU - I was diagnosed in late 23/early 24 - my docs didn't raise any red flags until I moved back to Montana - was in Indianapolis for years and my docs didn't say a word - my numbers started changing after my covid shot - so I honestly believe that is a big part of it - I am adopted with no health history. It took almost 6 months and many tests before they referred me to a hemotologist - but I now have the most amazing oncologist here in MT - recently my platelets have gone up, along with my B12 and LDH levels - been tired etc more than normal. Waiting for a message back from my doc. I do have the JAK2 mutation along with the CHEK2 - which puts me at higher risk for breast and colo-rectal cancers - just turned 56 and they say after 60 I am high risk - but if my numbers aren't horrible and I am still active and healthy, i will refuse the HU treatment.

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Replies to "@mdramsey48 Yes on interferon - I have been listening to many podcasts promoting it over HU..."

@jville42

It's not podcasts or AI that should guide your decision about treatment.

Listen to your oncologist. Only she or he knows what's best for you.

Sadly, our cancer is so rare that it's way over the heads of many general practitioners. This delays diagnosis for many of us. I'm so glad you have now found an experienced specialist.

ET is not something to ignore. It's what's causing your fatigue, and it puts you at higher risk of blood clots. Being active and healthy is always great, but no matter how much you exercise, you cannot undo the JAK mutation that causes ET.