@jville42 My platelets were generally between 680 and 771. They went down on HU and anagrelide but shot up quickly once I stopped taking them. I am considered high risk due to symptoms and an arterial clot after a hysterectomy in 2023. My platelets have been high for years but no one ever mentioned it until last year when I went to my PCP for a variety of symptoms. I was dx with breast cancer right after my ET dx so I had to go thru active treatment for that before I could start treating for my ET. I asked to see an MPN specialist but my onc asked me to give him a shot since he was already treating my BC. I agreed and then went thru hell for 3 mos. He said I was complex and referred me to a specialist. I cannot understand why MPN patients aren’t immediately sent to a specialist. And why aren’t interferons the first line of treatment since they can stop disease progression and potentially reverse it? Good luck to you! Do you have symptoms? I can’t remember if you said you did or not. You may have symptoms you didn’t recognize as related. I know I did!

@jville42 Oh! I am also very active and healthy. I can tell you that puts us way ahead of the game!❤️