← Return to Liver Transplant: What is the lowest dose of Tacrolimus anyone is on?

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Profile picture for Curses @kmlowe

I’m currently on 1.5mg total each day 1mg am, .5 in pm. This being said, the rate that the body metabolizes tacrolimus varies significantly. Even at this relatively low dose, my tacrolimus level can be as high as 8 or as low as 4 (which may be too low).

And, obviously, check with your team, maybe they’ll recommend getting your blood drawn more frequently to monitor more closely. I’m 10mos post transplant, so still get labs every two weeks, so they’re keeping an eye on me still.

Regards

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Replies to "I’m currently on 1.5mg total each day 1mg am, .5 in pm. This being said, the..."

@kmlowe Had a liver transplant 2.5 years ago. They started me on about 6 mg per day but I am now down to 1 mg per day (or on occasion 1.5 mg per day). Done .5 am and .5 pm. I don't think it can go lower than that as I think it metabolizes in about 12 hours so you would need the minimum of .5 twice a day about 12 hrs apart. Agree with the advice above and chat with them but go with whatever your care team deams. Best of luck.

@kmlowe That’s pretty low so they can obviously reduce down further. I guess it depends on Tac levels when I get them tested every 6 months. I think mine is steady around 5. It probably depends on your age, weight etc too. Thanks