@jc76 yes I could use research from Mayo.

@jc76
My dad has been taking Jaridance MWF for about six months now. I was hesitant to support this as it is quite expensive even in Southeast Asia where he lives most of the time, and I was wary as the "remodeling" pitch made me think more of new draperies than an improved heart. He started out taking it every day but his heart rate kept hitting "low" alarms while sleeping and sometimes when active. Now he takes it MWF, but the low heart rate alarms are still going off. Lowest so far has been 39, while asleep. He goes back to the cardiologist in a month.

He also takes Eliquis as a stroke preventative and lorezapam to help him sleep. He quit taking rosuvastatin as he felt terrible the entire time he was taking it, around five years.

He treadmills every other day for 50 minutes at max slope and around 4 mph, heart rate averaging around 115, about 80% of max for his age. He lifts light weights on the off days.

Recently it has been very hard to get his heart rate elevated while milling, so he starts out with jumping jacks until HR reaches 120, but "jumping" might not be the right word, his observation not mine.

He was diagnosed with heart failure about ten years ago, life expectancy pegged 2-5 years. But he was also told by a doctor friend that a treadmill could keep him alive longer. That's worked so far. Outside exercise is difficult here as it is too hot except for a few months per year. His goal to outlive his dogs. They are "inside" dogs, very rare here. Going back to the streets is not an option.

I would love to hear from anyone who has been taking Jardiance for a long time, but I think it's relatively new.