Have been on abrax and gemz for 22 months, 33 treatments, and not once had pain or nausia....only side effect was immediate loss of hair and fatigue that has slowed me down but not put me out. 80 yrs old, told we take the treatments that are every other week, forever or until I declare we stop. There is no cure of stage 4 pan. cancer/lungs just looking to slow it down, and outlive the 9 mo. average life span. I have done that with great quality of life, no pain no sicknesses,going to the casino still 3 times a week, and are 22 mos out from my diagnosis. I did have an internal stint surgery put in at time of my original diagnosis 22 mos ago for the bile duct blockage to stop the jaundace i had, It was an easy proceedure that keeps you out of pain. I have had no pain and no trouble with the internal stint My ca 19's are climbing in 22 mos from 6000 to 15000, so "the pill" is probably next, but maybe not, since I am doing so well. One thing, the every other week schedule is recommended for seniors, to lesson the side effects of the 2 common drugs used, AND we got anti nausia meds by intravenus for 15 min each time before the treatment, which probably helped. Is the cancer gone, no, no no, is it slowed up, yes yes yes, and quality of life is almost the same as it was before diagnosis. I have no ellusions, pan cancer is not curable, but at least for me it is at this time very bearable.