Pancreatic Cancer: Anyone have liver metastasis after Whipple?

I had a Whipple at Mayo Rochester in October 2024 as well and my scan last week showed two lesions on my liver, 2 cm each, consistent with metastatic disease. I am getting a biopsy on Wednesday this week. Otherwise, I feel great and was recovering well from my Whipple. My weight is steady, I have good energy and my blood work is good except for some elevation in alkaline phosphatase (ALP). My last scan in December was clear and my ctDNA test in January showed no tumor DNA and my CA 19 levels in December and February were at 4 (my tumor did not produce much CA 19)
@kbower1611 how are you doing and who are you seeing at Mayo ? How is the chemo working out and what does your onco recommend as next steps ?

@rajeshaji I had my whipple in Sept,2025 last chemo in Dec2025,went you the doctors this week and there were 2 lesions on my liver,having a biopsy on Aug 5,
I do feel great my weight is steady and have energy, don't know what to expect, but will take it one step at a time.

@memamary Hi and welcome to Mayo Connect. Sorry to hear about your post Whipple liver lesions. How were they found? Was it a follow up exam?

@tomrnnie .yes it was found at a MRI,I had at the beginning of July.

Hi, I was diagnosed July 2024 with PNET, had Whipple Dec 2024. subsequent PET Dotatate scans show 3 liver mets under 8mm. Have been on Lanreotide injections since Oct 2025, MRIs every 6 months and PET dotatate once a year. So far the mets are stable, one apparently disappeared.