@malebreastcancer47

I don't take all the medications your friends husband takes so cannot comment on the interactions. I do know carvedilol takes some time to get used to.

I do see one very important drug left off with the friend having heart failure (Entresto).

It is a fairly new medication that just went generic. Have your friend discuss Entresto with his cardiologist. I think going to Mayo is important for second opinion.

Your friend can always make an appointment with pharmacist and go over these medications with him/her and their interactions. I did this recently at Mayo and we went over all my medications, interaction, and when to take. We also went over my supplements and if should be taking or discarded. All looking for drug interactions and something a medical professional should do for you.