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Hydroxyurea causing mild anemia
Blood Cancers & Disorders | Last Active: 5 hours ago | Replies (15)Comment receiving replies
Thanks...I think my hemo doctor feels the higher dose caused the mild anemia and dropping one HU pill should correct the issue.
Was wondering if your other blood lines, RBC,WBC,HGB & HCT adjust over time to the HU increase.
It's a bit of a dance keeping the platelets suppressed and the other blood lines staying in the normal range. RBC & WBC have been low for 9 years on HU...BUT first time HGB & HCT went a little low out of the normal range.
My dr. wants it below 400. It was at 286 a week ago after she doubled the HU to 1000mg M-F and 500mg on Weekends. Now she's dropped it to 1000mg M-Th. And 500 MG F,Sat,Sun
Every time it creeps up to 400k we add a pill.
Started out 1 HU 500mg a day.
So in almost 9 years it's creeped back up to low 400K 5x.
Been doing this for almost 9 years...never had an issue with anemia.
Replies to "Thanks...I think my hemo doctor feels the higher dose caused the mild anemia and dropping one..."
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@mjfp49 good morning , I've been on HU for 10 months now! I'm treated at Baptist Cancer Center in Memphis TN. My Hematologist/oncologist has me on HU 1,000 every other day alternating 1,500 plus a baby aspirin every . I have to use a pill box to keep up with it. !!! He has noticed RBC going down as well as WBC. I go this Monday for a shot of Reblozyl every 3 weeks to get counts back up, I will be monitored carefully. Unfortunately he does not want to lower HU dose because it is at the level he feels it needs to be. don't know if this helps someone. In addition I just had a total hip replacement 2 weeks ago, doing well with that. He replaced the baby aspirin with Eliquis for 4 weeks 2.5 mg then back on baby aspirin.