Not Good News after prostate biospy when MRI didn't look too bad
Last month I had PSA of 5.23 when a few months earlier it was 3.2. Then they scheduled me for MRI of prostate. Did another PSA and it was down to 4.16, but still wanted the MRI. Report is below, doesn't look good PI-RADS 5. At one point they say in report Lesions (PI-RADS 3 or higher). If I understand it, it hasn't spread. Wish I could get a plan with doctor!
FINDINGS:
Prostate measurement: 5.7 x 5.0 x 4.9 cm Prostate volume: 68.75 cc PSA: 4.16 ng/mL PSA density: 0.06 ng/mL/cc
Peripheral zone: See below.
Transition zone: No index lesion. Stromal and glandular BPH nodules.
Lesions (PI-RADS 3 or higher):
Lesion # 1: Location: Left posterior peripheral zone extending from the base to the apex Size: 2.4 x 1.3 x 2.6 cm (5.83 cc). T2: T2
hypointense DWI: Marked restricted diffusion DCE: Focal early enhancement, positive Prostate margin: Abuts the capsule without
definite invasion Overall PI-RADS Score: 5/5
Prostatic capsule: Intact.
Neurovascular bundles: Not involved.
Seminal vesicles: Not involved.
Lymph nodes: No lymphadenopathy.
Bones: No acute osseous abnormality.
Other findings: Small fat-containing right inguinal hernia.
IMPRESSION:
1. The prostate gland measures 5.7 x 5.0 x 4.9 cm with volume of 68.75 cc. PSA density is 0.06 NG/mL/CC. 2. Lesion # 1: PI-
RADS 5 lesion in the left posterior peripheral zone extending from the base to the apex measures 5.83 cc. No frank extracapsular
extension. 3. No pelvic lymphadenopathy.
PI-RADS Category 5: Very high (clinically significant prostate cancer is highly likely to be present)
Really doesn't look to bad, one spot that hasn't spread!
Then Bad Update 2/10/2026
Well got biopsy yesterday and results today, doctor hasn't called, just sent biopsy results to MyChart.
The MRI showed only one Lesion like shown above. Had biopsy done yesterday, they did 3 from the Lesion and 6 from each side of prostate. I wondered why they did more biopsy that were outside the lesion, but didn't ask. Got report today- not good. The lesion look better than areas where MRI saw nothing. They took 15 samples total.
Results:
Final Diagnosis
View trends
A. Prostate, "LLB", biopsy:
Prostatic adenocarcinoma Gleason score 3+4=7 (Grade group 2) in 1 of 1 core, involving 30% of needle core tissue.
B. Prostate, "LMB", biopsy:
Prostatic adenocarcinoma Gleason score 4+3=7 (Grade group 3) in 1 of 1 core, involving 70% of needle core tissue
C. Prostate, "LLM", biopsy:
Prostatic adenocarcinoma Gleason score 3+4=7 (Grade group 2) in 1 of 1 core, involving 60% of needle core tissue.
D. Prostate, "LMM", biopsy:
Prostatic adenocarcinoma Gleason score 4+3=7 (Grade group 3) in 1 of 1 core, involving 60% of needle core tissue.
Large cribriform glands present.
E. Prostate, "LLA", biopsy:
Prostatic adenocarcinoma Gleason score 3+4=7 (Grade group 2) in 1 of 1 core, involving 60% of needle core tissue.
F. Prostate, "LMA", biopsy:
Prostatic adenocarcinoma Gleason score 3+4=7 (Grade group 2) in 1 of 1 core, involving 50% of needle core tissue.
G. Prostate, "RLB", biopsy:
Benign prostatic tissue.
H. Prostate, "RMB", biopsy:
Prostatic adenocarcinoma Gleason score 4+3=7 (Grade group 3) in 1 of 1 core, involving 10% of needle core tissue.
I. Prostate, "RLM", biopsy:
Benign prostatic tissue.
J. Prostate, "RMM", biopsy:
Prostatic adenocarcinoma Gleason score 4+3=7 (Grade group 3) in 1 of 1 core, involving 50% of needle core tissue
Large cribriform glands present.
K. Prostate, "RLA", biopsy:
Benign prostatic tissue.
L. Prostate, "RMA", biopsy:
Prostatic adenocarcinoma Gleason score 4+3=7 (Grade group 3) in 1 of 1 core, involving 25% of needle core tissue
M. Prostate, "ROI#1", biopsy:
Prostatic adenocarcinoma Gleason score 3+4=7 (Grade group 2) in 3 of 3 cores involving 70% of needle core tissue
Another thread I posted in a person said "You have a Gleason 4+3 7 BUT you have large cribriform and doctors a UCSF say that puts a 5 in your Gleason score." I believe he picked this up from the biopsy report. I don't know what a cribriform even is, it's not mention in report. From googling around it can only be determined by sieve-like or "Swiss cheese" appearance under a microscope and I don't see that in report? But this is all new to me. Doctors haven't talked to me yet, who knows when they will call or make appointment, took long time to get MRI and even longer to get the biopsy done. Sure were fast getting results, they said 7 - 10 days and they gave them to me the next day. Kind of wish they didn't give me results prior to talking with me.
My first thought is just get the thing cut out, not sure how that is done, as seems they got to leave something in there for urine to flow threw. So they couldn't take 100 percent of prostate out. Then I read about nerve sparing or not and not sure what that means. No doctors have discussed this with me yet. Seems if they take it out there shouldn't be any prostate cancer left? But then I read where people get it out and still have a PSA level, so like I said earlier, they must leave some in there, even when they call it total. Had to drive 150 miles to get MRI and biopsy They could have done that in Topeka, but KUMC is ranked as number 50 in top of prostate treatment so I went there Topeka doesn't have a Proton device, that would be back up to KUMC 150 miles RT. One of those radiations therapy is only a few days, not 30 some days. They do have SBRT radiation in Topeka, but I know of someone who had SBRT or maybe it was IMRT and it screwed up several other organs around the prostate, like bladder, kidneys and intestines.
Then some tell me I am lucky to have them all in grade group 2 or 3. But seems like I had a lot of them (12 of the 15) . So I would guess if they did 25 biopsy I could have had more grade group 2 or 3.
All confusing and stressful, other that this I am 78 years old healthy as a horse- no other issues and very active. Loss of what to do and all the different radiation types, that why just getting the pesky thing cut out of there, but seems they still leave some in.
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I agree, it really clear there is a swollen up area going up at an angle in the groin and it is sore. I can understand the Express Care doctor saying what she did as she knew I was going to urologist next day. She just assured me that it was not something that required an ER visit and be sure to followup with appointment next day.
But the urologist response was just not right! I know he was busy and behind from an emergency surgery and office full of patients, but still poor service. He suppose to be a good surgeon, but he is not a people person. Maybe that is why he is in a practice by himself and not in a group. There are not really many urology surgeons in Topeka, I think 4? Then not all of them will deal with cancer. The best one that everyone liked retired.
I made appt with PCP for 8/6/26, he can be difficult, but I can usually talk him into getting a test done.
It just seem reasonable to at least get a ultrasound. I may even make an appointment with his APRN, she likes me and I bet she would have more testing done if I asked. I might be able to see her Monday or Wednesday, those are only days she works as she has young child at home ans another one due in 2 months.
Sure wish I had doctors and staff like my wife did at KUMC for her breast cancer. I might add in Topeka, they were terrible and auguring among themselves (surgeon, radiologist and pathologist) what to do for her cancer and where it was located, that is why we went to KUMC.
@diverjer
An ultrasound is the cheapest and easiest compared to Ct scans and MRI’s. Ultrasounds are so common and commonly used right in a urologist office to see if your bladder is empty, but those ultrasound’s are set up with parameters for bladder urine readings. The point is their should be no reason not to get the groin ultrasound as it is so easy.
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1 ReactionI agree, maybe I should have been more forceful. But I knew he was in a bad mood dressed up in his scrubs with lots of people waiting so I didn't do much arguing. All he kept talking about was the mesh was behind all that area swelling and not on the outside surface where swelling was? It was almost like, yeah there's something not right but it's not my problem from anything I did.
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1 Reaction@diverjer Yeah, but how much swelling is on the OTHER side of the mesh causing all the pain??
My advice is to just leave this surgeon behind - he can no longer be of any use to you and you are wasting your time, OK?
You need testing - as the other members have suggested - and a good hernia surgeon to evaluate what’s going on. It could be a number of things but you won’t know anything constructive if you keep relying on the cancer surgeon for answers.
His whole job right now is to say ‘not my fault’ and to tell you what it’s NOT…not what it IS!!
Phil
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4 Reactions@heavyphil
Great advice. Also prostate surgery is so intricate that most prostate surgeons who do considerable number of surgeries focus on that. Generally the all around surgeon does hernia repair, gallbladder, appendectomy. I recall my surgeon saying he would never repair a hernia at the same time and does not do that when doing prostate surgery. I would imagine the prostate surgeon likely does not do enough hernia surgeries to be as skilled as the general surgeon doing them regularly. Also I would think while the patient is recovering and then having issues in the abdomen do you really know then what is causing it, effects from the prostate surgery or hernia surgery.
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3 ReactionsWhile I'm sitting around the day thinking I remember about 5 years ago that surgeon said I had inguinal hernia and he could fix it real easy, at that time I told him no I've had it a long time it don't bother.
Anyway today I seen my PA-C, and she seemed to take things serious. She's had me do three different blood tests which all looked good. And also scheduled a sonogram to be done. Got all three blood tests back and they were all within normal, but the AST and ALT were high end of normal. I pressed the trend button and for years I was right in middle of green bar of normal or lower, starting May not long after surgery the last two test have claimed to just barely in normal green bar. That swollen area is about 2 inches below liver, but I doubt that is why ALT and Ast rising. But makes me wonder.
It was nice having someone actually take the swollen area seriously. Sometimes I wonder if the PA-C and APRN don't listen better than today's MDs?
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1 ReactionIt is a personal choice , but I did radical prostatectomy and am very happy with results. Some in my support group (local in Va) who had radiation have had problems with bowel pain.
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1 ReactionIf I were you I'd read the book "The Key to Prostate Cancer" by Dr Mark Scholz. They have chapters by various experts on every aspect and therapy for PC. Also go to the website PCRI.org (Prostate cancer research institute), and watch some of the videos. They have videos covering most things you need to know. Anybody who is in or near Southern California should get an appointment with Prostate Oncology Specialist clinic in Marina Del Rey.
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1 ReactionWell they just don't know why that area is swollen up, blood test looked fine and the sonographic findings were fine. The guy seem to do a good job checking me out, he had 2 students there teaching them so he spent a lot of time looking around.
MPRESSION:
No sonographic findings to explain the patient's symptoms.
Electronically signed by Neal A Hall, MD
DT: 7/30/2026 11:42 AM
Narrative
EXAM: Ultrasound abdomen single organ
INDICATION: Right groin swelling, hx right inguinal hernia repair with mesh
TECHNIQUE: Real-time ultrasound of the right groin region was performed with permanent freeze-frame documentation.
COMPARISON: None
FINDINGS:
No visible hernia is present within the right inguinal region. Incidental small morphologically normal small lymph node is present.
I am still not happy that surgeon put mesh in there when I was fine with the inguinal hernia for last 40 years. But after going through things I signed, I found the following in small print. "unforeseen condition may be reveled that necessitate an extension of the initial procedure or a different procedure than that set forth above. " Even more small print that said a student may assist! All this was in small print where the actual procedure I wanted was in very large hand printed form.
Anyway they still don't know why I have swollen area that is a bit painful. One positive I finely got referral for pelvic therapy, but they can't see me until Aug 10 and that is for what sounds like an assessment only.
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1 Reaction@diverjer So even lymphedema was ruled out? The lymph node is ‘normal’ but I am not sure that its presence (and size) rules out lymphedema. You should ask about this.
Phil
https://canceracademy.org/category/blog/
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