Hi @garyann2554, welcome to Mayo Clinic Connect. I’m so sorry to hear how much your husband has been suffering. It sounds like this has become much more than an occasional discomfort, especially with the significant weight loss, severe pain, difficulty eating and drinking, constipation, and not being able to sleep because of the pain.

I’d like to invite @musicbart back into the discussion in case they have an update since starting this conversation.

While members can share their own experiences, the symptoms you describe sound significant. If your husband is rapidly losing weight, unable to eat or drink comfortably, or his pain is worsening despite treatment, I would encourage contacting his healthcare team again as soon as possible, or seeking urgent medical evaluation if the pain is severe or he cannot keep food or fluids down.

Has he had any recent imaging, such as a CT scan, or has he been evaluated by a gastroenterologist? Knowing what testing has already been done may help members share experiences that are more relevant.