I wouldn't call it normal for CLL, but it also isn't particularly unusual. I have noticed increased sensitivity of my skin and more contact dermatitis likely caused by a compromised immune system. If you think of CLL as a cancer of the immune system it makes a lot of sense and explains why we get more skin issues. I would recommend the shingles vaccine. Shingles can be absolutely awful and can cause permanent nerve damage. Again, your immune system usually keeps the latent chicken pox virus that causes shingles in check in healthy adults, but our immune system isn't healthy so we have a higher risk of shingles.