@gravity3 I take 100mg immediate release Progesterone at bedtime. Sometimes, I add in 50mg extended released that I get from a compounding pharmacy. For Estradiol, I use generic Divigel which comes in premeasured packets to be rubbed on behind the knees, sides and anywhere the skin is thin. I don't remember the dose but I use 1-2 packets daily to keep my uncomfortable physical symptoms away. It still isn't always enough for anxiety.

@gravity3 I was on the 0.025 mg estradiol patch twice weekly for about 5 months, then increased to the 0.05 mg patch for about 4 months before discontinuing it. I also took 100 mg of progesterone nightly. I started this regimen when I was 57. I’ll be 59 this month and plan to resume HRT now that I’m no longer taking an antidepressant