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karyn23 avatar

Evenity + HRT synergy?

Osteoporosis & Bone Health | Last Active: Jul 20 2:38pm | Replies (12)

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I too am curious if anyone’s doctor is prescribing HRT alongside Tymlos or Forteo. I was under the assumption it would help, but there seem to be no studies or data to support this idea. Only that it could help maintain bone afterward. But if you have to follow up with Fosamax or similar anyway, do we really know HRT will add to this?

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Replies to "I too am curious if anyone’s doctor is prescribing HRT alongside Tymlos or Forteo. I was..."

@lp30 It seems - from my brief glance at a couple of studies - that both HRT and bisphosphonates cause cell death of osteoclasts, which would explain why both are classified as anti-resorptive. (Disclaimer: I have zero background in biochem! Just a lay person trying to learn.) If both therapies have the same action, it would seem that either could be employed. An important question must be which gives better results.

@lp30 I’m 75 and I just asked my GYN about HRT with my bone condition and she said the HRT at my age might kill me. Didn’t say why!

@lp30 I am a 70-year-old woman with an early subtotal hysterectomy (one ovary removed and the other was left a small part of it) at age 34. A month ago, I went through rigorous consultation with my cardiologist, and he cleared me for HRT/ transdermal estradiol \/patch starting with the smallest dose, 0.025 mg, and going up to 0.05 mg if my heart and blood pressure are OK. I started Teriparatide/Forteo 2 days ago. Currently, I am experiencing "heavy chest" after each injection, and my blood pressure is a little bit high. I think this is a Forteo side effect and hope to adjust to it.