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ANDROGEN DEPRIVATION.THERAPHY FOR SHORT OR LONG TERM?
Prostate Cancer | Last Active: 1 day ago | Replies (40)Comment receiving replies
@zonanaa
Other comments may say that, but test results I have seen from clinical trials have shown that for people with aggressive prostate cancer they need to stay on it for 24 months or longer..
I attend nine advanced prostate cancer online meetings a month. I run into many people whose doctors have recommended 24 months or even a lifetime ADT (like I have been on for Eight years) When they have Aggressive cases.
It’s definitely a lot nicer to not have an aggressive case.
Replies to "@zonanaa Other comments may say that, but test results I have seen from clinical trials have..."
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@jeffmarc
Yes, so far that was the belief. Before even non aggressive cancers were having at least 6 mos of ADT with RT for salvage radiation.
This new study that Dr. Kishan explained (in provided link above) showed that no ADT was necessary for any salvage that started before PSA 0.5 .
We had consultations recently with him and even for my husband that is high risk and nodes involved his opinion was that more than 6 mos of ADT is not necessary. Intensification with added Nubeqa yes, but more than 6 mos would not possibly have additional benefit. Now it is up to us to decide, of course.
There is definitely VERY STRONG trend with shortening ADT in all cases. My personal opinion is that new lines of drugs like Nubeqa have very strong effect on cancer progression during treatment and if added to regular ADT they change the game plan. BUT, that is my "amateur" opinion. However - there is a tectonic shift in protocols for ADT usage.