Good luck with your daughter’s infusion and journey to a cancer free future as I believe Car-T will provide.
My wife was diagnosed with large B cell non Hodgkin Lymphoma in lymph nodes in her neck in the fall of 2023. After 5 R-CHOP chemo treatments and 17 days of radiation treatment she was declared cancer free in early 2024. However in January of 2025 she was experiencing rapidly depleting speech, visual and balance issues. An MRI found 3 spots in the base of her brain and brain stem, in areas that could not be biopsied.
The Oncologists at University of Penn assumed it was a metastasis of the neck Lymphoma. After 4 chemo treatments of Methaltrexate (SP?), which took a toll on her kidneys, they decided to offer her the CART-T treatment. The published potential side affects gave us reason to be very concerned! We decided to proceed anyway and I can now tell you it was amazing in regard to how it completely eliminated all signs of any masses in her brain.
We stayed in a suite close to the hospital for 4 weeks and had blood drawn every other day. She had a low grade (<100) fever for a few days and minor “fuzzy brain” periods but no serious discomfort. She is now 1-1/4 year since the infusion of the modified T cells and has had 4 completely clear MRI brain scans and is feeling great at age 85%+!
Good luck and God bless to you and your family!