@mistymar
Thanks for the advice and in particular thanks for sharing your experience. with degree and quality of pain. I was struck when you wrote "Just general every day [bone and joint pain] but also the moving areas of acute pain like being stabbed." The extent of the acute pain I have experienced on AI (letrazole to date) has been striking and your description reminded me of my own experience. The pain is not in any ways similar to the sensation of MSK pain I have experienced in the past pre letrazole. When I move some areas it feels like what I can only describe as biting pain- not aching, not sore, not strained or overused. In fact certain movements amke me cry out in pain. I have been off letrazole since the end of May ( three months on it) . since then had 16 sessions radiation. Had to take naproxen/ppi vimovo to be able to hold arms in proper position for radiation . Of course raised blood BP as did letrazole. Sleep disturbance acute as well. I am now planning on exploring the role of pre-existing fibromyalgia in CONJUNCTION with breast cancer treatment as an explanation for the persistent acute long term and QOL threatening symptoms. Previous Fibro was not particularly disrupting.