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MCI/Alzheimer's Helping? - Report Your LiO Effects +/-
Early Dementia & Mild Cognitive Impairment (MCI) | Last Active: 8 hours ago | Replies (6)Comment receiving replies
The other topic mentioned above is "Have MCI, sharing new intel re Lithium Orotate" at this Mayo Connect link:
https://connect.mayoclinic.org/discussion/new-intel-re-lithium-orotate/
It's a fabulous source of info and discussion about the 2025 study, and much more. After reading some Reddit discussions, I found it quite helpful to read people's reports on their experiences so I'm hoping we can expand on that here too. I was particularly interested to read this Reddit topic:
https://www.reddit.com/r/Alzheimers/comments/1oje8j4/comment/nmdvest/
where someone noted that one brand of 5mg LiO we've been taking also lists the far less effective Carbonate ingredient (LiC not LiO). If the LiO ingredient is mixed with less expensive LiC, it could have far less benefit. My understanding is that we're understandably discouraged (prohibited?) from posting brand names here.
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@plus So to start off with my own report:
My wife was diagnosed with Mild Cognitive Impairment (MCI) caused by Alzheimer's Disease (AD), a few months ago. After reading the aforementioned Harvard study, I looked for more info regarding any potential side effects or downsides to taking low-dose (1 to 20mg) Lithium Orotate. Finding no negatives, and with moderately strong potential upsides I started both of us on 1mg daily.
At first with breakfast, then adding another dose at bedtime. I've read that there may be some chance that the relatively high acid level in the human stomach might reduce the amount of LiO reaching the brain where it's needed. I've also read that stomach acid's irrelevant with LiO, but am still doing the morning (lowest stomach acid level before breakfast) and night (typically 4-6 hours after dinner). Our current total daily dose is 12mg/day, but 10mg of that's apparently at least partly LiC so I'll be changing brand on the 5mg portion asap.
As to effects, no downside or side effects. Fairly soon after starting LiO I noted mild improvement but not enough to be sure it's from the LiO. Lately I'm getting more confident of positive benefit. My wife was unable to draw a clock in the initial neurology test, and unable to read an analog clock at home. I've not tested her ability to draw one yet, but she can now tell the time again. Her memory has definitely improved somewhat, and her cognition has too.
Anyone else have a sense of whether or not LiO is helping?