Anti-convulsants/anti-epileptics affect bone density

Posted by blueskies1530 @blueskies1530, 11 hours ago

I take two anti-convulsants and was told they may have contributed to my lower bone density. I was diagnosed with osteoporosis at 49. I take Lyrica/Pregabalin for nerve damage and fibromyalgia. And I take Trileptal/Oxcarbazepine for mood stability. I'm wondering if I should try to lower the dose on each of them. Has anyone else been told their lower T score could be caused by their anti-convulsant?

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gently | @gently | 8 hours ago

blueskies1530, this class of medications (AEDs) is recognized for causing low bone density. You might be able to take a medication to counteract the loss. Teriparatide (Forteo) is approved for this purpose. It is sometimes prescribed before the loss. While there is no interaction between teriparatide and these other drugs, your doctor would want to monitor your serum levels.
https://mnepilepsy.org/patient-information/bone-health-and-epilepsy-are-your-bones-brittle/
Best wishes