Reclast aftermath pain

You may also want to go up to the search function and type in reclast. There are a number of discussions that have been ongoing. Sorry that you are in pain.

I had one Reclast infusion and my knee swelled up so badly I couldn’t walk for a week. Thankfully resolved with ice/rest. Was sore generally and achy for months . It’s been 3 years and I’m back to normal. Took over 6 months to feel better.

Taking Tymlos now ( only taking half dose) and thinking I will take a half dose of reclast at the end.
Everyone is different and cannot tolerate these drugs.

To your question: exercise seems to always help get things moving and less side effects. Seems to speed up metabolism of the Tymlos anyway.
Good luck with this and let us know how you’re doing.

Are you taking calcium regularly? Reclast (like Prolia) will interfere with your bones from supplying calcium to your blood, so if you are not getting regular, daily intake of calcium, your body get's low on calcium that leads to all kinds of issues including body aches and pains (search "hypocalcemia symptoms") . Perhaps have your doctor check your fasting calcium and vitamin D levels. If you have low vitamin D, your body cannot absorb calcium that you eat / take which is also a problem while on Reclast. Just guessing here but worth looking into.

Kay, some patients are getting relief from a 5 day Metrol dose pack. No one want to give steroids with osteoporosis, but I've read that the 5 day low dose is easier on your bones than the inflammation. It's a wonder that your endocrinologist doesn't suspect the Reclast infusion. I'm pretty sure it is. I include this description from the gentleman who ran the final clinical trials for Reclast.
"When a special category of phagocytic T-cells, called gamma-delta T-cells, encounter the zoledronic acid, they engulf it, just like an osteoclast will engulf alendronate or zoledronic bound to the bone surface. And just like an osteoclast that engulfs a N_BP undergoes apoptosis (programmed cell death), the gamma-delta T-cells that engulfs a N-BP also undergoes apoptosis. The difference is, when a gamma-delta T-cell undergoes apoptosis, it releases inflammatory cytokines, such as IL-1, IL-6, and TNF-alpha, just like when it encounters a flu virus. And these inflammatory cytokines mediate the temperature rise and myalgias, just as with a flu infection."
Cytokines can activate a continuous cycle of inflammation, which I think is happening with longer term reactions to Reclast. You might ask your primary for the steroid.
Don't feel like you should answer. I'm asking without a question mark. Do you have any active autoimmune systems.
In Korea they are having success with giving a dose of steroid before the injection.

@michaellavacot Are you replying to me? If so, yes was taking vit D/K2 and calcium was being monitored. It was a sudden and immediate reaction to the infusion.