Hello @saurabh, I'm glad to read that your mother will start the targeted therapy, Tagrisso/osimertinib. These types of medications have been game-changers in extending the lives of lung cancer patients. I take a different targeted therapy for a different type of mutation (ALK, alectinib, 6 years), and I believe that I wouldn't be here today without these medications. These drugs don't cure the cancer, but they can be very effective for years at a time for the fortunate patients. Were her doctors hopeful? Did they provide answers to your questions? Is she taking the osimertinib along with chemotherapy, or did they stop the chemo? How are YOU doing through this period of diagnosis and early treatment? It's not an easy path.