Back in the day, and I mean really quite some (30-40) years ago when I was first diagnosed with asthma at Walter Reed, I was put on a maintenance regimen of theophylline and singulair and am still taking them to this day. I am aware that theophylline is no longer prescribed these days but I have remained a user so I thought it might be worth mentioning since you seem to be experiencing less than satisfactory results from the meds currently out there.