PSA undetectable but testosterone remains negligible

Posted by anosmic1 @anosmic1, 9 hours ago

Mostly good news from today's PSA test 7 months after the end of radiation. I'm age 68, Gleason 9, had RP in November 2024, 6-month Lupron injection in October (9 months ago) and 39 radiation treatments ending in February.

PSA is undetectable (<0.01) but testosterone remains almost nonexistent at <12. Reference range is reported as 240-1022. Saw the radiation oncologist today and he seems surprised that the testosterone score is so low still and that I continue to have hot flashes, probably 10-12 a day. He didn't take any new steps.

Next appointments are October with the urologist/surgeon and January with Red Onc.

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just had my latest PSA ( finishing 1 yrs of ADt) it was <.02 and Testostrone was < 12 but I still have hot flashes altho not as intense as 6-8 months ago.

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It is normal for it to take 3-6 months for testosterone to return after the stated expiration of Lupron shots. You still have a good chance it will return in a few more months. Unlikely to be as high as pre-ADT levels.

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Did you only have 1 Lupron injection (9 months ago) or did you have more than one injection and that was your most recent one?

What was your testosterone level prior to your Lupron injection(s)?

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I started Orgovyx on 12/05/23 and finished on 06/05/24. Here are my values.
Date Testosterone
11/3/2023 517
12/14/2023 27
3/28/2024 14
6/28/2024 482
10/7/2024 372
1/8/2025 466
5/21/2025 590
11/18/2025 722

Stay Strong Brother, We Got This.

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