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After 1 year on Tymlos only a slight DECREASE in BMD. Please help.
I am 61 years old, T score for spine is -3.1, hip -2.2 (via a DEXA scan). I have been taking Tymlos for 12 months. I have been following my bmd via REM scans. The REM scans at 6 month and 12 month show slightly decreasing BMD. I will take my 12 month DEXA scan next week. I am so scared my DEXA score will also show a decrease in my BMD. I understand one cannot compare DEXA results with REM results, but there is a definite trend in my REM scan scores. I am also very worried that Tymlos for some reason is just not working for me. I have had all my tests: vit D, calcium, PTH, p1NP1 (95!) - all my test results look good, but my BMD is not increasing! Is there a chance it will increase in year 2 of taking tymlos (12 months - 24 months). I read that some people have delayed reactions. Has anyone else here experienced this??? I am so single with no children to help me. I am so scared I will fracture my spine and become disabled. Please help me....
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Latest research on REMS shows that it is not using much of the ultrasound measurements, 90% just demographic data. I also had self-pay REMS done, but I no longer believe the results.
Demographic determinants of REMS-derived BMD and fragility score
https://link.springer.com/article/10.1007/s00198-026-07960-4
EXCERPT: "Conclusions
REMS-BMD and fragility scores are strongly influenced by demographic inputs, particularly age and weight. The REMS output therefore reflects an assessment of BMD and fracture risk strongly based on demographic parameters, rather than an ultrasound-based direct skeletal measurement. ..."
REMS Bone Scan (Echolight): What the Evidence Says About This DEXA Alternative
https://melioguide.com/osteoporosis-prevention/rems-bone-scan/
EXCERPT: "A 2026 study in Osteoporosis International (Chan et al.) found that age and weight alone explain the vast majority of REMS output variance. The coloured bars show how much of each result is predicted by demographics alone. ..."
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2 ReactionsYes, the journey is not an easy one. However, as one doctor told me, the alternative is not a good one. When it is all over, that is when you will realize it was worth it! Hang in there!
Sending healing energy and prayers!