Low Testosterone

Posted by ava11 @ava11, 1 day ago

It has been 15months since I stopped ORGOVYX after being on it for 1 year. My PSA stayed at 0.03. My Testosterone during ADT dropped to 8. But after I stopped ADT, it went up to 85. But now it is 46. PSA is 0.03 My Gleason Score 9 but cancer was in the gland and I was treated with 5 sessions of SBRT at UCLA. I am 90. Any one in this situation?

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@jeffmarc

Studies I have read support your comments, but some studies also indicate that age is also a major influence. When above 80, like me, recovery from Lupron is less likely and slower. Some doctors question the use of ADT's after age 80.

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@pesquallie
Yep, you do bring up an important issue, The older you get the less likely your testosterone will come back at all, Much less to normal level levels.

As mentioned by by Doctor Weber in his PCa commentary

The extent to which T is suppressed depends on a patient’s age and the duration of anti-
androgen exposure, and both those factors also influence the rate of T recovery after ADT is
ceased. At a T level of <230 ng/dL a man is said to be “hypogonadal” and symptoms from a
diminished T commence - to different degrees in different men. After 3 - 6 months duration of
Lupron or Relugolix treatment 65% of men will still be below <230 ng/dL at 12 months after
stopping.

If someone has a serious case of prostate cancer at 80+ It may make sense to use ADT, It depends on the person, their health and their mental attitude. You can always give testosterone injections after treatment is completed.

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