@tkdesign,
parathyroid glands control calcium in the blood. When we have low serum calcium, parathyroid hormone is released, which signals release of calcium from our storehouse of calcium--the bones.
Forteo is a segment 1-34 of parathyroid hormone. When we inject the 20mcgs we by pass the gland and trick our bodies into thinking our serum calcium is low. Calcium is pulled from our bones and from the digestive tract even back from the kidneys were it is slated for elimination. Our bodies recognize the flood of serum calcium as a physiological emergency, and recruit osteoblasts to renew that lost bone.
Our parathyroid glands produce little hormone while we are on the pth drugs, as your pth labs will attest.
The reaction to the flood of calcium happens within seconds of the injection. And just as quickly the calcium is directed to the endangered bones. To speed the distribution our blood vessels widen, and our hearts beat faster and stronger.
Within 4 to 6 hours calcium is normalized in the serum. Except with kidney disease. It can take 16 to 24 hours with reduced kidney function. With reduced function the calcium isn't eliminated as well as it form can form calcific obstructions even further reducing kidney flow.
Your endocrinologist will monitor calcium, pth, and egfr during your treatment.
Anyone having serum calcium labs withing four hours of the injection will have elevated serum calcium.
I take K2 and magnesium orotate 2 hours before the injection that pulls all that calcium into the blood stream. I wonder if it helps keep calcium out of my vascular tissue and back into my bones.